• Indication
  • Pharmacokinetic Properties
  • Contraindications
  • Adverse Reaction
  • Interaction
  • Dosage
Skin and soft tissue infections
Eradication of helicobacter pylori
Unlike erythromycin, Annyclarit is acid stable, so it can be token orally without being protected from gastric acids. It is readily absorbed and diffused into most tissues and phagocytes, annyclarit is actively transported to the site of infection. Its concentration in the tissues con be over 10 times higher than in plasma. It has a fairly rapid first pass metabolism in the liver, with an elimination half-life of about 3 to 4 hours.
Annyclarit should be used with caution if the patient hos liver or kidney disease, certain heart problems, or tokes drugs that might cause certain heart problems (e.g. QT prolongation or bradycardia), or an electrolyte imbalance (e.g low potassium or sodium levels)
Diarrhea nausea, abdominal pain end vomiting. It can also co use headaches, insomnia, abnormal liver function tests. Allergic reactions include rashes and anaphylaxis, jaundice, ototoxicity.
This is possible interaction between annyclarit with medicines for heart diseases (digoxin, disopyramide), allergies (terfenadine, astemizole), asthma (theophyline), epilepsy (carbamazepine) or HIV (ritovir)
Adults: 250~500mg to be taken 3-4 times doily
Prophylaxis for Streptococci: 250mg (to be taken twice doily)
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